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LH


Formal name: Luteinising hormone

The Test Sample

What is being tested?

Luteinising hormone (LH) is produced by the pituitary gland in the brain. Control of LH production is a complex system involving hormones produced by the gonads (ovaries or testes), the pituitary gland and the hypothalamus, such as gonadotrophin-releasing hormone (GnRH).

Women’s menstrual cycles are divided into 2 phases, the follicular and luteal, by a mid-cycle surge of follicle-stimulating hormone (FSH) and LH. The high level of LH (and FSH) at mid-cycle triggers ovulation (release of the egg from the ovary). LH also stimulates the ovaries to produce other hormones, mainly oestradiol. Oestradiol helps the pituitary gland to control the production of LH. At the time of the menopause, the ovaries stop functioning and LH levels rise.

In men, LH stimulates the Leydig cells in the testes to produce testosterone. LH levels are relatively constant in men after puberty.

In infants and children, LH levels rise shortly after birth and then fall to very low levels (by 6 months in boys and 1-2 years in girls). At about 6-8 years, levels again rise with the beginning of puberty and the development of secondary sexual characteristics.

How is the sample collected for testing?

A blood sample is taken by needle from a vein in the arm.